On the 2001 English Channel 5 show The People of New York vs Jerry Sadowitz, Vos was the bouncer, often performing his own skits. In 2004, Vos released his first DVD. Entitled Vos, the self-produced stand-up comedy special consisted of an unedited 55 minute performance from a single camera angle, recorded off the monitor at the Stress Factory in New Brunswick, New Jersey, with a plain black cover with the word “Vos” printed in sans-serif font on it. He also released a CD entitled “I’m Killing Here”. He has the distinction of being the first white comedian to perform on Def Comedy Jam. Vos placed third on the first season of NBC‘s Last Comic Standing and starred in the show’s first and third seasons.
In September 2005, Vos married comedian Bonnie McFarlane, who competed on the second season of Last Comic Standing. Together they have a daughter, Katrina Lynn Vos, born on July 31, 2007. He is also a frequent guest on the Opie and Anthony radio program on XM Satellite Radio, often substituting for Jim Norton. He has also hosted Saturday night broadcasts with McFarlane.